Computational Biomedicine for Translational Research

October 6-7, 2014

organized by the

Joint Research Center for Computational Biomedicine, RWTH Aachen University



About the Symposium

Computational Biomedicine for Translational Research brings together the stakeholders of Computational Biomedicine: The symposium will provide a forum where industrial researchers and clinicians can meet and discuss with academic researchers from medicine, biology and computational sciences.

One year after opening the Joint Research Center for Computational Biomedicine, the symposium aims to present the technological state of the art for successful translational applications. Talks and discussions will focus on unmet needs and scientific challenges towards a roadmap chartering the path to realize the promises of data and modeling for the benefit of medicine.



Monday, October 6

10:00 am   Welcoming (with coffee & refreshments)

10:30 am   Opening

Prof. Stefan Uhlig, Dean of Medical School, RWTH Aachen 

10:35 am   Introductory Remarks

Prof. Andreas Schuppert, JRC Computational Biomedicine, RWTH Aachen


Modelling of organisms – the key to future medicine?

Chair: Prof. Andreas Schuppert

10:40 am   Applications of Modeling & Simulation in Pharmaceutical Development

Dr. Joerg Lippert, Bayer Health Care AG

11:20 am   The Virtual Liver Network: a multidisciplinary, multilevel challenge for Systems Biology

Adriano Henney, Programme Director, German Virtual Liver Network 

12:00 pm   Spatio-temporal tissue reconstruction with cellular resolutions: challenges, tools, lessons

Prof. Peter Kohl, Imperial College, London 

12:40 pm   Pitch for posters

01:00 pm   Lunch


Integrative modelling – a multidisciplinary challenge

Chair: Dr. Ingo Gaida

02:00 pm   Integrating omics data in cohort studies: beyond univariate analyses

Prof. Fabian Theis, TU Munich

02:40 pm   Predictive quantitative modeling for stem cell engineering

Dr. Franz-Josef Mueller, CAU Kiel

03:20 pm   Bayesian PBPK

Dr. Linus Goerlitz, Bayer Technology Services GmbH 

04:00 pm   Data intensive discovery in the life sciences

Prof. Jacob de Vlieg, Bayer Crop Science AG

04:40 pm   Poster Session (with coffee & refreshments)

06:30 pm   Conference Dinner at Ratskeller Aachen

Address by Prof. Dr. E. Schmachtenberg, Rector of RWTH Aachen


Tuesday, October 7

Modelling towards a therapy-centric approach

Chair: Prof. Stefan Uhlig

09:00 am   Challenges in Systems Analysis of Complex Pathophysiologies

Prof. Douglas Lauffenburger, MIT

09:40 am   Decoding Network Dynamics in Cancer

Prof. Rune Linding, DTU Lyngby

10:20 am   Coffee break

10:40 am   Modelling aspects of tumour growth - from individual scale to multi-scale

Prof. Philip Maini, Oxford University

11:20 am   Therapy centric modeling at JRC

Prof. Tim Brümmendorf, UKA Aachen, Prof. Andreas Schuppert, RWTH Aachen

12:00 pm  Panel discussion: How to realize the benefits of data and models – needs & challenges

Prof. Maini, Prof. Kohl, Prof. Lauffenburger, Prof. Uhlig, Prof. Schuppert

12:30 pm   Closing remarks

Prof. Andreas Schuppert, RWTH Aachen

01:00 pm   Lunch

Location and travel

The Symposium is organized by the JRC and will take place at the University Clinic Aachen (UKA), Pauwelsstrasse 30, 52074 Aachen, Germany.

All talks are held in the Seminar Room (level 0E, corrridor 46, room 04); signs will guide you to the Symposium.

Arriving by car From the motorway A4, take exit no. 2 Aachen-Laurensberg. Turn right, then continue towards Maastricht and follow the signs to Uniklinik. Parking (pays) is in front of the UKA building. Further information is available on the UKA website.

Arriving by bus: UKA is served by several buses, the stop name is Uniklinik. From Aachen main station, take the 3B bus that leaves from stop H2, across the road from the station building. From the city center, take the lines 33 (towards Vaals, Bloemendaal, NL) or 73 (towards Uniklinik) for direct connections to UKA. For further information and bus timetables, see the website of Deutsche Bahn or the ASEAG website (German only).



Organization and contact

Please ensure to confirm your attendance by August 31, 2014 by contacting

Mrs. Hülya Ulu-Esser
Phone: +49 241 8099392
Fax: +49 241 80628498

For general enquiries, please contact

Prof. Dr. Andreas Schuppert
Phone: +49 241 8099202