Phase Transitions in Living Systems

October 24th - October 25th, 2018

organized by the

Joint Research Center for Computational Biomedicine, RWTH Aachen University



About the Workshop

Five years after its opening, the Joint Research Center for Computational Biomedicine hosts this workshop to bring together academic and industrial researchers as well as clinicians.

Scientific presentations, poster sessions and discussions will focus on current trends and challenges in the field of Phase Transitions in Living Systems and hopefully inspire new innovative approaches and collaborations towards a better understanding of the dynamics of these systems.




Wednesday, October 24th

11:30 - 13:00    Arrival, Registration & Lunch

13:00 - 13:30   Welcome Address

Joint Research Center for Computational Biomedicine - Today & Tomorrow

Prof. Dr. Andreas Schuppert, RWTH Aachen University

13:30 - 15:15    Session I: 3 Talks

Understanding drug effects by integration of perturbation data and computational models

Prof. Dr. Julio Saez-Rodriguez, Heidelberg University

Stem cell differentiation as a phase transition 

Prof. Dr. Ben MacArthur, University of Southampton

Data driven model updates for inverse problems with applications in magnetic particle imaging

Prof. Dr. Peter Maass, University of Bremen / FhG

15:15 - 15:30    Poster Pitch Presentations

15:30 - 16:30   Poster Session & Coffee Break

16:30 - 18:30   Session II: 3 Talks

Predicting the effect of interventions with causal graphical models

Prof. Dr. Marloes Maathuis, ETH Zürich

From biochemical reaction networks to dynamics

Prof. Dr. Bernold Fiedler, FU Berlin

Critical transitions and early warning signals in disease pathogenesis – Can we apply concepts from physics and ecology?

Prof. Dr. Rudi Balling, LCSB Luxembourg


Thursday, October 25th

09:00 - 10:45   Session III: 3 Talks

Data Analyses and Modeling in Clinical Development – integrative learning from diverse data sources

Dr. Jörg Lippert, Bayer AG Leverkusen

Computer-Based Modeling of Immunotherapy Strategies in Human Colorectal Cancer

Dr. Jakob Nikolas Kather, UKA Aachen

Myeloproliferative neoplasms (MPN): a group of model disorders for phase transition in chronic diseases

Prof. Dr. Tim Brümmendorf, UKA Aachen University

10:45 - 11:15    Coffee Break

11:15 - 12:30    Session IV: 2 Talks

Modelling Metastable Regimes and Tipping Points of Biochemical Networks using Tropical Geometry Methods 

Dr. Satya Swarup Samal, RWTH Aachen University

Bridging phase transition to therapeutic intervention through quantitative systems pharmacology

Dr. Neil Benson, Certara

12:30 - 13:00    Closing Remarks

Prof. Dr. Andreas Schuppert, RWTH Aachen University

13:00 - 14:00    Closing Discussion, Lunch & Farewell



Participation at the workshop is free of charge, but registration is required.

Please use this form to register.


Location and travel

The Symposium is organized by the JRC-COMBINE and will take place at Super C, RWTH Aachen University, Templergraben 57, 52062 Aachen, Germany.

All talks are held in Generali-Saal (level 6); signs will guide you to the Symposium.


Arriving by car  Super C of RWTH Aachen University can be reached via autobahn A4 from Heerlen/Eindhoven or Cologne, A544 towards Aachen Europaplatz, and A44 from Düsseldorf/Mönchengladbach or Liege/Brussels.

Arriving by bus:  Super C of RWTH Aachen University can be reached from Aachen Central Station without switching lines by taking any of the following buses: 4, 7, 17, 24, 27, 33, 37, 47, 73, 77, 147 and 173 and getting off at busstop Driescher Gässchen. You can also take line 13B from Aachen Central Station and get off at busstop Technische Hochschule. For further information and bus timetables, see the website of Deutsche Bahn or the ASEAG website (German only).


Organization and contact

Please ensure to confirm your attendance with the registration form or via mail.

For organisational enquiries, please contact

Mrs. Hülya Ulu-Esser
Phone: +49 241 80 85890
Fax: +49 241 80 3385890

For general enquiries, please contact

Prof. Dr. Andreas Schuppert
Phone: +49 241 80 85891

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